陈宇星｜中国科学技术大学｜学者主页

精选作品

期刊论文

2025

Structural insights into human ABCA7-mediated lipid transport.

Shuling Fang, Liang Wang, Meng-Ting Cheng, Da Xu, Zhi-Peng Chen, Jie Wang, Wenli Liao, Yan-Yan Li, Cong-Zhao Zhou, Wen-Tao Hou, Yuxing Chen

Structure

DOI

2024

Structural insights into human ABCD3-mediated peroxisomal acyl-CoA translocation

Yang Li, Zhi-Peng Chen, Danny Xu, Liang Wang, Meng-Ting Cheng, Cong-Zhao Zhou, Yuxing Chen, Wen-Tao Hou

Cell Discovery

DOI

2024

Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain

Yao-Xu Mao, Zhi-Peng Chen, Liang Wang, Jie Wang, Cong-Zhao Zhou, Wen-Tao Hou, Yuxing Chen

Nature Communications

DOI

2023

Human SIDT1 mediates dsRNA uptake via its phospholipase activity

Cai-Rong Sun, Da Xu, Fengrui Yang, Zhuanghao Hou, Yuyao Luo, Chen-Yu Zhang, Shan Ge, Guang-Ming Huang, Xue-song Yao, Yuxing Chen, Qiong Li, Cong-Zhao Zhou

Cell Research

DOI

2023

Structural insights into human ABCC4-mediated transport of platelet agonist and antagonist

Yu Chen, Liang Wang, Wen-Tao Hou, Zhihui Zha, Kang Xu, Cong-Zhao Zhou, Qiong Li, Yuxing Chen

Nature Cardiovascular Research

DOI

2023

Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate‐binding pocket

Jie Wang, Xu Li, Fang Wang, Meng-Ting Cheng, Yao-Xu Mao, Shuling Fang, Liang Wang, Cong-Zhao Zhou, Wen-Tao Hou, Yuxing Chen

EMBO Journal

DOI

2022

Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets

Liang Wang, Wen-Tao Hou, Jie Wang, Danny Xu, Cong Guo, Linfeng Sun, K. Ruan, Cong-Zhao Zhou, Yuxing Chen

Cell Research

DOI

2022

Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding

Mengting Cheng, Yu Chen, Zhi-Peng Chen, Xin Liu, Zhi Zhang, Yuxing Chen, Wen-Tao Hou, Cong-Zhao Zhou

Proceedings of the National Academy of Sciences of the United States of America

DOI

2022

Structure and transport mechanism of the human cholesterol transporter ABCG1.

Danny Xu, Yanyan Li, Fengrui Yang, Cai-Rong Sun, Jin-Heng Pan, Liang Wang, Zhi-Peng Chen, Shuling Fang, Xue-Biao Yao, Wen-Tao Hou, Cong-Zhao Zhou, Yuxing Chen

Cell Reports

DOI

2022

Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1

Zhi-Peng Chen, Danny Xu, Liang Wang, Yao-Xu Mao, Yang Li, Meng-Ting Cheng, Cong-Zhao Zhou, Wen-Tao Hou, Yuxing Chen

Nature Communications

DOI

2022

Plastic structures for diverse substrates: A revisit of human ABC transporters

Wen-Tao Hou, Danny Xu, Liang Wang, Yu Chen, Zhi-Peng Chen, Cong-Zhao Zhou, Yuxing Chen

Proteins: Structure, Function, and Bioinformatics

DOI

2020

Cryo-EM structure of human bile salts exporter ABCB11

Liang Wang, Wen-Tao Hou, Li Chen, Yong-Liang Jiang, Danny Xu, Lin-Feng Sun, Cong-Zhao Zhou, Yuxing Chen

Cell Research

DOI

2019

Cryo-EM structure of human lysosomal cobalamin exporter ABCD4

Danny Xu, Zhang Feng, Wen-Tao Hou, Yong-Liang Jiang, Liang Wang, Lin-Feng Sun, Cong-Zhao Zhou, Yuxing Chen

Cell Research

DOI

2016

Crystal structure of yeast monothiol glutaredoxin Grx6 in complex with a glutathione-coordinated [2Fe–2S] cluster

Mohnad Abdalla, Yao-Hua Dai, C. Chi, Wang Cheng, D. Cao, K. Zhou, W. Ali, Yuxing Chen, Cong-Zhao Zhou

Acta Crystallographica Section F Structural Biology Communications

DOI

2015

Structural basis for receptor recognition and pore formation of a zebrafish aerolysin‐like protein

Ning Jia, Nan Liu, Wang Cheng, Yong-Liang Jiang, Hui Sun, Lan‐Lan Chen, Jun-Hui Peng, Yonghui Zhang, Yue-He Ding, Zhihui Zhang, Xuejuan Wang, G. Cai, Junfeng Wang, M. Dong, Zhi Zhang, Hui Wu, Hong-Wei Wang, Yuxing Chen, Cong-Zhao Zhou

EMBO Reports

DOI

2010

Human and viral nucleoside/nucleotide kinases involved in antiviral drug activation: structural and catalytic properties.

D. Deville-Bonne, C. El Amri, P. Meyer, Yuxing Chen, L. Agrofoglio, J. Janin

Antiviral Research

DOI

2009

Nucleoside Diphosphate Kinase and the Activation of Antiviral Phosphonate Analogs of Nucleotides: Binding Mode and Phosphorylation of Tenofovir Derivatives

K. Koch, Yuxing Chen, Joy Y. Feng, K. Borroto-Esoda, D. Deville-Bonne, Sarah Gallois-Montbrun, J. Janin, S. Moréra

Nucleosides, Nucleotides & Nucleic Acids

DOI

2005

NDP kinase in complex with adenosine phosphonoacetic acid

Yuxing Chen, S. Moréra, C. Pasti, A. Angusti, N. Solaroli, M. Véron, J. Janin, S. Manfredini, D. Deville-Bonne

DOI

2005

Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase.

Yuxing Chen, S. Moréra, C. Pasti, Angela Angusti, Nicola Solaroli, M. Véron, J. Janin, S. Manfredini, Dominique Deville-Bonne

Medicinal chemistry

DOI

2004

Developments in Structural Genomics: Protein Purification and Function Interpretation

Cong-Zhao Zhou, Yuxing Chen

DOI

2003

Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases.

Yuxing Chen, S. Gallois-Montbrun, B. Schneider, M. Véron, S. Moréra, D. Deville-Bonne, J. Janin

Journal of Molecular Biology

DOI

2003

NDP kinase mutant (H122G) complex with RTP

S. Gallois-Montbrun, Yuxing Chen, H. Dutartre, S. Moréra, C. Guerreiro, L. Mulard, B. Schneider, J. Janin, B. Canard, M. Véron, D. Deville-Bonne

DOI

2003

Structural analysis of the activation of ribavirin analogs by NDP kinase: comparison with other ribavirin targets.

S. Gallois-Montbrun, Yuxing Chen, H. Dutartre, M. Sophys, S. Moréra, C. Guerreiro, B. Schneider, L. Mulard, J. Janin, M. Véron, D. Deville-Bonne, B. Canard

Molecular Pharmacology

DOI

2002

X‐ray structure of Mycobacterium tuberculosis nucleoside diphosphate kinase

Yuxing Chen, S. Moréra, Julia Mocan, I. Lascu, J. Janin

Proteins: Structure, Function, and Bioinformatics

DOI

2002

Improving Nucleoside Diphosphate Kinase for Antiviral Nucleotide Analogs Activation*

S. Gallois-Montbrun, B. Schneider, Yuxing Chen, Veronique Giacomoni-Fernandes, L. Mulard, S. Moréra, J. Janin, D. Deville-Bonne, M. Véron

Journal of Biological Chemistry

DOI

2002

Mycobacterium tuberculosis Nucleoside Diphosphate Kinase

Yuxing Chen, S. Moréra, I. Lascu, J. Janin

DOI

2002

NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP

S. Gallois-Montbrun, B. Schneider, Yuxing Chen, Veronique Giacomoni-Fernandes, L. Mulard, S. Moréra, J. Janin, D. Deville-Bonne, M. Véron

DOI

2002

HCV polymerase inhibition by ribose modified ribavirin analogues

H. Dutartre, M. Sophys, S. Gallois-Montbrun, Yuxing Chen, S. Moréra, C. Guerreiro, B. Schneider, L. Mulard, J. Janin, M. Véron, D. ville-Bonne, B. Canard

会议论文

2016

Structural insights into the transcriptional regulation of carbon/nitrogen metabolism homeostasis in Synechocystis

Yong-Liang Jiang, Xue-Ping Wang, Hui Sun, Dong-Dong Cao, Wang Cheng, Yuxing Chen, Cong-Zhao Zhou

《中国晶体学会第六届学术年会暨会员代表大会（大分子晶体学分会）论文摘要集》

2013

Seeing the N-terminal shuttle domain of yeast Erv1: structural insights into the electron transfer process of Mia40-Erv1 disulfide relay system

郭鹏超，马金頔，江永亮，王姝洁，余小杰，陈宇星，周丛照

《第四届中国结构生物学学术讨论会论文摘要集》

2013

Structure of Streptococcal glycosyltransferase GtfA reveals that the novel intervening domain DUF1975 auguments its activity by modulating the interaction with GtfB

Wei-Wei Shi, Yong-Liang Jiang, Yi-Hu Yang, Qiu-Yan Shao, Hong-Bo Yang, Cong-Zhao Zhou, Yuxing Chen

《第四届中国结构生物学学术讨论会》

2013

Negative feedback regulation of O-acetylserine sulfhydrylase from Microcystis aeruginosa 7806

Mo Lu, Bo-Ying Xu, Kang Zhou, Yong-Liang Jiang, Wang Cheng, Yuxing Chen, Cong-Zhao Zhou

《第四届中国结构生物学学术讨论会论文摘要集》

2013

Structural Basis for Cell Wall Remodeling by a Pneumococcal Peptidoglycan Hydrolase LytB

Xiao-Hui Bai, Hui-Jie Chen, Yong-Liang Jiang, Wang Cheng, Zhensong Wen, Qiong Li, Jing-Ren Zhang, Cong-Zhao Zhou, Yuxing Chen

《第一届国际暨第十三次中国生物物理学术大会摘要集——S1冷冻电镜与结构生物学》

2012

酿酒酵母Ap 4 A磷酸化酶Apa2的结构酶学研究

江永亮，侯文韬，周丛照，陈宇星

《中国晶体学会第五届全国会员代表大会暨学术大会（大分子分会场）》

2012